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COVID-19 in conjunction with diabetes and obesity (both characterized by severe insulin resistance) has severe clinical consequences 742,743

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For example, a dual synergistic nanoreactor incorporating dihydroquercetin and platinum nanocatalysts within mannose-modified OL-NP demonstrated robust neuroprotection by reducing neuronal injury and modulating microglial activation toward an anti-inflammatory M2 phenotype [299]

Front Genet 2022;13:1094474

[DOI] [PMC free article] [PubMed] [Google Scholar] 154.Kang Y.P., Mockabee-Macias A., Jiang C., Falzone A., Prieto-Farigua N., Stone E., Harris I.S., DeNicola G.M