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Authorship confirmation/contribution statement K Martino: Writing Original Draft, Data Curation, Investigation, Visualization A Nakhre: Writing Original Draft, Investigation RM Demarest: Conceptualization, Resources, Supervision (MDCK scatter assay) DM Devilbiss Conceptualization, Formal Analysis, Funding Acquisition, Methodology, Resources, Supervision, Validation, Writing Review & Editing Author(s) disclosure (Conflict of Interest) statement(s) The authors declare that they have no competing financial interests related to the work reported in this paper

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A total of 1407 randomized adults, with a mean baseline body weight of 113 kg, were randomized to once-weekly semaglutide 7.2 mg, semaglutide 2.4 mg, or placebo over 72 weeks, in conjunction with lifestyle intervention

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