Finally, astaxanthin is produced by the oxidation of -carotene and catalyzed by astaxanthin synthase (crtS) (Kizer et al., 2008)
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doi: 10.1016/j.immuni.2022.07.008 6 HadadiEet al
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This pathway is determined by vitamin B2 status, indicated by plasma riboflavin, and B6 status, indicated by circulating PLP
HYF showed superior efficacy compared to donepezil, while JYF reduced tau protein levels, providing comparable benefits to standard ChEIs (Wang et al., 2020)