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In vivo electrophysiological recording During the experiment, the mice were first anesthetized with 4% isoflurane (i.r) in the chamber

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Enhanced activity of IDO enzymes (IDO-1 and IDO-2) shifts tryptophan metabolism towards the kynurenine pathway, leading to increased concentrations of kynurenic acid (KYNA) within the CNS (216220)

doi: 10.1113/JP276488 110 DalbramEBasseALZierathJRTreebakJT

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