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Proper dose calculation is especially important when working with research-grade materials where concentrations may differ from commercial preparations
Maintaining the same batch COA number throughout a study eliminates a potential variable in research data
(PubMed) Clarke R, Smith AD, Jobst KA, Refsum H, Sutton L, Ueland PM
Commercial research material is therefore commonly supplied with an oppositely charged counterion, such as iodide, to form an electrically neutral salt
Since mouse microbiome profiles often highly correlate with body weight and fat composition, this study was designed to test whether the cecal microbiomes of DIO mice treated with NNMTi and LD were comparable to the microbiomes of age-matched lean counterparts and distinct from microbiomes of DIO mice maintained on a high-fat Western diet (WD) or subjected to LD switch alone