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Both AMPK activation and ketone body production signal the body to prioritize fat oxidation over glucose metabolism

Combined enrichment of neuromelanin granules and synaptosomes from human substantia nigra pars compacta tissue for proteomic analysis

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[10] [11] Phase 2 trial data published in the New England Journal of Medicine in 2023 (Jastreboff et al.) demonstrated substantial effects on body weight and metabolic parameters, though the full benefitrisk profile is still being established in ongoing Phase 3 trials

Epitalon Preparation Prof Khavinson (Saint Petersburg, Russia) kindly provided the tested peptide Epitalon, which was dissolved in water at a stock concentration of 100 g/mL, then further diluted to prepare the three concentrations for testing (20, 40, and 60 ng/mL)