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MM: Data curation, Writingoriginal draft

Retatrutide is still investigational in 2026, so it is still in trials and has no FDA approval for prescription sale

For individuals with type 2 diabetes , the incretin effect is reduced, though GLP-1 secretion itself may be normal while another incretin hormone (GIP) is more impaired

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Oral semaglutide 14 mg was associated with an incremental cost-effectiveness ratio (ICER) of EUR 1339 per QALY gained versus empagliflozin and was considered dominant (clinically superior and cost saving) versus sitagliptin and liraglutide

For the most accurate and current pricing, its advisable to consult directly with pharmacies and consider all available options, including discounts and patient assistance programs.