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Other GLP-1 receptor agonists, including liraglutide and semaglutide, are now being evaluated clinically across several substance use disorder domains (alcohol, nicotine, cocaine, and opioid use disorder), with multiple trials ongoing (NCT05895643, NCT07227948, NCT06924697 at ClinicalTrials.gov) or recently completed (Klausen et al., 2022

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This Phase 1 trial, completed on an accelerated timeline, marks a key milestone in validating both the safety and translational potential of Hanmis next generation triple agonist in humans

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