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Mechanistically, liraglutide and semaglutide decreased LV hypertrophy and fibrosis, and improved diastolic dysfunction, lung congestion, and exercise capacity

Nolte, W

If HbA1c rises to 58 mmol/mol (7.5%) or higher, reinforce lifestyle advice and intensify medicines with a target of (7.0%) 53 mmol/mol

While its superior efficacy in adults suggests potential relevance for adolescent obesity treatment, direct extrapolation to younger populations is not yet supported by robust pediatric evidence

Journal of Clinical Investigation, 135(21)

Secondly, they often contain stimulant ingredients that can cause psychiatric side effects like heart palpitations and anxiety