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Patients with diabetes often develop cardiomyopathy, which makes them more vulnerable to heart failure and increases their risk of death from myocardial infarction, regardless of whether they have a vascular disease

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Lys105 is a GSH and enzyme activator in the GSSCys assay In a first set of experiments, we analysed the effects of the Lys105 replacements on the steady-state kinetics at variable GSSCys and GSH concentrations

An oral alternative to weekly injections could dramatically expand the addressable market and create barriers to entry for competitors still stuck in the injectable paradigm

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