Self-assembling peptide scaffolds Self-assembling peptides (SAPs) that form hydrogel scaffolds represent a convergence of biomaterial science and peptide therapeutics
GLP-1 RA therapy significantly improved both exercise capacity and HRQoL in individuals with obesity-related HFpEF regardless of diabetes status, but had no effect on these parameters in in HFrEF patients
Given the recent results of the CREDENCE trial, many patients will also be treated with an SGLT2-inhibitor, allowing the trial to study the combined use of these agents on renal outcomes
Most people begin to feel the effects of an IV within a few hours and continue to feel those effects for several days
Fungal infection involvement in primary biliary cirrhosis: A review of 2 cases
Key Takeaways Anti-inflammatory peptides target NF-kB, cytokine, and oxidative stress pathways without broad immunosuppression KPV, BPC-157, TB-500, and GHK-Cu are the most widely researched peptides for inflammation Mechanism of action varies some modulate NF-kB directly, others reduce inflammation through mitochondrial or hormonal pathways Research peptides are not approved for human anti-inflammatory use and should stay in a research-only context Chronic inflammation is a root driver of metabolic disease, autoimmune conditions, neurodegeneration, and accelerated aging
