Effects of GLP-1 receptor agonists on fracture risk in humans The STEP program, consisting of phase 3 randomized controlled trials, has examined the effectiveness of semaglutide (Wegovy) in treating obesity [18, 19]
[74] Gastrointestinal effects could include nausea, dyspepsia, and increased risk of peptic ulceration, particularly with concurrent use of other ulcerogenic medications
-Cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment
GLP-1 receptor agonistsmost notably semaglutide (marketed by Novo Nordisk as Ozempic and Wegovy) and tirzepatide (marketed by Eli Lilly as Mounjaro and Zepbound)have experienced extraordinary demand as treatments for type 2 diabetes and obesity
Melanotan 2 and Appetite Regulation Many studies indicate that MT-II is involved in regulation of appetite and energy expenditure
Competing Interests The authors declare that there are no competing interests associated with the manuscript