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In the Billon 2023 paper, a single 25 mg/kg intraperitoneal dose in mice was enough to induce an acute aerobic exercise transcriptional signature in muscle within hours

rn *Conclusion* rn IGF-LR3 is a synthetic analog of IGF-1 with potential therapeutic applications in muscle growth and tissue repair

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The current study and approach has several limitations

The real-world implications are significant

Vitamin B12: Involved in the methylation cycle, which is a precursor to how our bodies create glutathione