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Cryotherapy risks primarily involve direct cold injury (frostbite) from excessive exposure duration or temperature

Growth hormone-related therapies should be avoided in active malignancy, as growth hormone may promote tumor growth

In general, researchers consider copper peptides safe for most healthy adults to use

Journal (Drug Design, Development and Therapy, Apr 30, 2015, 9, 24852499)

Redness or Irritation Mild swelling or discomfort at the injection site

Elevated LOXL2 expression in estrogen receptor-negative breast tumors is strongly associated with unfavorable outcomes, including poor prognosis, decreased overall survival, and reduced metastasis-free survival, suggesting that LOXL2 could serve as a valuable prognostic marker for metastasis in breast cancer cases