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These patients require therapies that enhance lipolysis, upregulate energy expenditure, and optimize cellular metabolism
Food intake in animal studies remained unchanged despite the compound producing significant fat loss
NNMT (nicotinamide N-methyltransferase) is an enzyme that methylates nicotinamide, diverting it from NAD+ synthesis
SGLT-2 inhibitors and thiazolidinediones may also be used concurrently, though patients should be monitored for any unexpected interactions or adverse effects
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