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In clinical trials, patients on the 25mg maintenance dose lost an average of around 13.6% of their body weight over 64 weeks alongside a reduced calorie diet and increased physical activity

Diabetes Care 2014;37(6):15441553

It increases fullness, slows gastric emptying, and helps regulate blood sugar levels

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Refer to the above section on Lantus for information on switching to insulin glargine from other insulin regimens

Some patients find that IV hydration therapy helps manage the dehydration and fatigue that can accompany the early adjustment period, particularly if nausea makes oral hydration challenging