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[DOI] [PubMed] [Google Scholar] 57.Kindel T.L., Wang A.Y., Wadhwa A., et al

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Figure 3 5 Strategies for osteoporosis management: gutbone axis targeted 5.1 FMT, probiotics, and prebiotics 5.1.1 FMT As a novel technique of organ transplantation, FMT involves transferring fecal microbiota from healthy donors to recipients to modify disturbed intestinal ecology, whose efficacy in treating digestive diseases such as Clostridioides difficile infection (CDI) ( Clostridium IV and XIVa isolated from healthy mice increased the number of systemic and lamina propria Treg cells when transplanted into germ-free mice, which in turn affected osteoclast genesis through the secretion of IL-4, IL-10, and TGF-

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