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The absolute number depends on three factors: starting body composition, dose escalation speed, and the size of the calorie deficit the drug creates

Dry yourself off with a clean towel

Quillard T, Arajo HA, Franck G, Shvartz E, Sukhova G, Libby P

The study is interesting as a computer science paper, but the methods and findings dont stand up to medical scientific scrutiny, says Yuval Pinto, MD, an obesity and family medicine doctor at Johns Hopkins Medicine in Baltimore

5 , e583e583 (2015)

Real-world effectiveness Studies examining real-world outcomes show that results are typically somewhat lower than in clinical trials but still significant: A 2025 Cleveland Clinic study found average weight loss of 10-15% in routine clinical practice (compared to 15-22% in trials)