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The mechanism of action of curcumin against tumors is facilitated by three different mechanisms: (i) downregulation of anti-apoptotic proteins which leads to the induction of apoptosis in tumor cells and upregulation of tumor suppressor genes (e.g., p53) (ii) downregulation of MMPs (matrix metalloproteinase), which prevents tumor invasion and (iii) the anti-inflammatory effect which increases its potency against tumors

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131 The production of RONS increases the sensitivity of cells to genotoxic drugs by decreasing the activity of DNA-PKcs, hindering repair processes, and leading to the accumulation of DSBs

Vitamin B12 helps convert food into energy, boosts metabolism, and aids in the breakdown of fats and proteins

This side effect stems from rapid blood pressure changes and metabolic shifts as your body adapts to medication

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