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Semaglutide Start: 0.25 mg once weekly Increase to: 0.5 mg weekly Then: 1 mg weekly Maintenance: up to 1.72.4 mg weekly, depending on tolerance Tirzepatide Start: 2.5 mg once weekly Increase to: 5 mg weekly Then: 7.5 mg Then: 10 mg Then: 12.5 mg Maximum: 15 mg weekly Retatrutide (Currently follows dosing schedules used in clinical studies.) Start: 12 mg once weekly Gradually increase to: 4 mg Then: 8 mg Then: 12 mg weekly Your provider will determine the safest dose progression based on your response and tolerance

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While exenatide (Byetta, Bydureon) was previously approved, these products have been discontinued in the US market

The statements and conclusions in each manuscript are solely those of the study authors and do not necessarily reflect the Associations policy or position

10.1016/j.cmet.2023.11.009 115 XiaL.OyangL.LinJ.TanS.HanY.WuN.et al (2021)

Postmenopausal women face particularly high UTI risk because declining estrogen levels thin the vaginal and urethral tissues, reduce protective Lactobacillus populations, and alter urinary pH