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The information presented here should not replace professional medical judgment or create a doctor-patient relationship.

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Studies have shown that tamoxifen resistance is associated with IGFBP-1 accumulation and that the overexpression of IGFBP-1 promotes tamoxifen resistance in breast cancer cells by activating the ERK pathway, which can be reversed by knocking down IGFBP-1 (134)

IGF-1 LR3 is the preferred choice when sustained systemic exposure is the research objective

Patients should maintain adequate hydration and seek medical attention if they notice concerning changes

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