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In controlled laboratory research models, IGF-1 LR3 binds to the insulin-like growth factor-1 receptor (IGF-1R), initiating downstream signaling cascades commonly associated with PI3K/Akt and MAPK/ERK pathway activation under defined experimental conditions

Blood Transfus 15:182187

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It is hypothesized that onset of MASLD is triggered by high fat diet which induces an increase in FFAs and LPS which are derived from the gut anaerobic bacteria (114, 136)

Tea catechin consumption reduces circulating oxidized low-density lipoprotein

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