Given that portal delivery of insulin, which has the potential to completely restore IGF-I levels in type 1 diabetes (70, 71, 87), remains an experimental treatment, rhIGF-1 treatment to restore circulating IGF-I and suppress GH and decrease insulin needs appears to be the most feasible approach to take (88)
The dose-response between 3 and 5 sessions is encouraging
Yang Y, Liu F, Lu R, Jia J
Managing Side Effects of GLP-1 Treatment in the UK Whilst swollen lymph nodes are not a recognised side effect of GLP-1 medications, these drugs do have a well-characterised adverse effect profile that patients and healthcare professionals should monitor
Research has shown that simvastatin can indirectly inhibit the mTOR pathway [21], activate the AMPK pathway [22], and modulate the SREBPs pathway [23]
Nature (2007) 445(7130):84350