Because the peptide is bio-identical, systemic side effects are rare
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The study discovered that the liver-protective effect of OFG does not rely on the colonization of live bacteria but is achieved by increasing the levels of SCFAs such as acetic acid, propionic acid, and butyric acid in the gut, among which butyric acid is the core effector molecule (Fig
Limitations and future perspectives The use of an antibiotic potentiator in combination with antibiotics is still in the development stage
"Make sure the needles are clean, and nice and sharp - and replace them as necessary
Since the valinomycin synthetase Vlm shows the same genetic architecture as Ces, it is tempting to speculate that the novel mechanism of non-ribosomal peptide assembly proposed in this study is not a specificity of the cereulide synthetase but a more common logic for biosynthesis of ester bond containing NRPS products, thereby contributing to biodiversity of natural depsipeptide products
