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While gastrointestinal symptoms (nausea, vomiting, diarrhea, constipation) affect many patients initially, severe or persistent symptoms may necessitate dose adjustment, temporary dose reduction, or consideration of alternative therapies

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there needs to be more research on that. For some, the drugs effects on satiety and taste are welcome changes that make it easier to eat less

Excess adipose tissue particularly visceral fat is associated with reduced testosterone levels and impaired fertility in men, making effective weight management especially relevant to male health