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Koehle, M

Methods Systematic searches were conducted in PubMed, Scopus, Web of Science, Embase, Cochrane Library, and trial registries

However, although trials have shown the drugs to be safe and effective, they are not without their side-effects most commonly nausea, vomiting, diarrhoea, constipation and decreased appetite

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Overall, the data published on APAP protein adducts in human studies suggest that this biomarker is highly specific and sensitive for the detection of APAP liver injury