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18 Among these factors, mitochondria dysfunction is regarded as one of the tremendous determinants in driving aging

Abstract Glucagon-like peptide-1 (GLP-1) is an incretin hormone released from gut enteroendocrine cells that modulates glucose metabolism by controlling insulin excretion and glucagon secretion and inhibits gastric emptying leading to decreased food intake, thus limiting weight gain

Chew NWS, Mehta A, Goh RSJ, Zhang A, Chen Y, Chong B, et al

Thus, late compared to early-onset depression may be associated with greater AD pathology

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KCl elicited a small yet significant increase in GLP-1 content in the supernatant of OB explants from RD mice exposed to 1 mM glucose (Supplementary Fig