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1 Genetics and declining renal function primarily drive gout development not diet Once labelled the disease of kings due to its perceived association with food and alcohol overconsumption, diet is now recognised as a less significant risk factor for gout development

Reprod Biol Endocrinol 22 , 138 (2024)

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They work through different mechanisms, have very different clinical research behind them, and are suited to somewhat different situations

Brain diseases linked to oxidative stress [363] change the GSH/GSSG ratio and thereby automatically affect the copper homeostasis, as GSH is the immediate partner, along with various chaperones, that takes Cu(I) from the transporter

The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies