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Do not inject a double dose to make up for a missed one

Designing future studies may require careful attention to which endpoint is primary, as that will dictate whether a lower, moderate, or higher dose is emphasised

Treatment depends on the severity of the condition and can range from improved oral hygiene to professional dental care

Faivre E, Gault VA, Thorens B, Hlscher C

doi: 10.1056/NEJMra0901217 120 HsuR.-J.YuW.-C.PengG.-R.YeC.-H.HuS

Additionally, the bias in patient selection across the literature raises the probability that improvements in systemic metabolic function, rather than direct immunomodulation, may underlie the observed improvements in psoriatic skin lesions