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Annu Rev Immunol 2001

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Marketing unapproved drugs: The FDA issued warning letters to companies that marketed compounded GLP-1 medications with claims that went beyond what is permissible for compounded products

Superimposing a tonic pharmacological brake on top of this feedback system creates competing signals, and it would be unsurprising if intestinal feedback partially normalized emptying over time even while the drug is present

The trade-off for the low price is simplicity: no berberine, no probiotic, so cravings tied to glucose swings may linger