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The recurring findings were that the substances are not well characterised, that human evidence of effectiveness is thin or absent for the proposed routes of administration, and that immunogenicity risk has not been assessed

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128 Introduction of a W104A mutation in the fused GHBP prevented intra- and inter-molecular binding

Caffeine in the diet: country-level consumption and guidelines

Most trials were too short and too small to demonstrate disease modification with statistical rigor

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