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Diarrhea: Both semaglutide and L-carnitine have been associated with occasional diarrhea, particularly when first starting treatment

Foundayo demonstrated 12.4% weight loss over 72 weeks

TRIUMPH-3 (Adults with severe obesity and established cardiovascular disease, with or without Type 2 Diabetes) * Up to 22.6% mean weight loss (55.8 lbs / 25.3 kg) at 80 weeks

Lilly now stands alone with a viable oral GLP-1 candidate in late stage development

Proper reconstitution requires a 1:1 to 2:1 water-to-powder ratio, sterile handling to prevent contamination, and immediate refrigeration at 28C after mixing to preserve the peptide structure for up to 28 days