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Exosome surface labeling with a chimeric peptide (C16K-protoporphyrin IX-PKKKRKV) comprising an alkyl chain (C16), photosensitizer (protoporphyrin IX), and nuclear localization signal peptide (PKKKRKV) can enhance the nuclear delivery of the photosensitizer and efficiently inhibit tumor growth via photodynamic therapy 41
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In addition, we observed changes in the expression of critical glutathione-related genes in the caudate nucleus of patients who were asymptomatic for HD and iSPNs of patients with grade 24 HD (Fig
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Their incidence increases with dose but typically decreases over time as the body adapts to receptor activation
Its ability to prevent bacterial growth allows for multi-dose usage from a single vial, enhancing its practicality in healthcare settings
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