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In various healthcare settings, acute kidney disease (AKD) has seen a rising incidence, with associated heightened risks of all-cause mortality, end-stage kidney disease, and chronic kidney disease (CKD)

The additional GIP receptor activity in tirzepatide does not appear to add thyroid risk, as GIP receptors are not significantly expressed on human thyroid C-cells

Questions remain One significant limitation of the study was that the team compared people who had taken GLP-1s with people of similar body mass who had never been on the drugs

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For example, if cravings start creeping back after being under control, it might mean your current dose isnt as effective anymore