20 Similarly, A phase 2 trial of 320 patients with biopsy-confirmed MASH found that daily subcutaneous semaglutide (0.4 mg) achieved steatohepatitis resolution without fibrosis progression in 59% of patients vs
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However, topline results released by NovoNordisk stated that their two phase 3 trials investigating once-daily oral semaglutide in early-stage Alzheimers disease (clinical trial numbers NCT04777396 and NCT04777409) did not confirm the superiority of semaglutide versus placebo in reducing the progression of Alzheimers disease, as measured by the change in Clinical Dementia Rating Sum of Boxes score compared with baseline
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