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Laboratory mice Biozzi ABH mice were originally purchased from Envigo and bred in-house under SPF conditions in individually ventilated cages in temperature controlled (21 C) animal facilities with 14/10 h light/dark cycles and a 55% humidity-controlled environment

Avoid chronic high dose supplementation unless supervised by a healthcare provider

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Eli Lillys retatrutide (LY3437943), the leading triple agonist, advanced from promising phase 2 results into phase 3 trials

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The most common sites were the maxillary and mandibular anterior alveolus, followed by the lingual aspect of the posterior mandible and the hard palate