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The trial included 17,604 people who received either weekly Wegovy or dummy injections (placebo) for up to 5 years

The drug stays active for nearly seven days , which is why it only needs to be injected weekly, as opposed to daily, like liraglutide

One recent study demonstrated that semaglutide inhibits neutrophil activation in epicardial fat and their adhesion to endothelial cells [38]

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Some pharmacies compound semaglutide with B12 at specific ratios designed to maintain adequate levels throughout treatment