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APOE4 tends to: * Bind lipids differently * Increase LDL particle oxidation susceptibility * Promote greater vascular inflammation * Be associated with higher cardiovascular and neurodegenerative risk It is not simply a cholesterol gene. It's a lipid transport and oxidative stress gene

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But curcumin has notoriously poor bioavailability, meaning very little of what you swallow actually reaches your bloodstream

Several companies, including Boehringer Ingelheim and AstraZeneca for specific listings, voluntarily delisted patents following FTC notice, which is evidence that some listings were either genuinely improper or that the litigation risk of defending them outweighed the 30-month stay benefit

RK: Investigation, Resources, Writing original draft