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Sulfur burping , one of the more unpleasant side effects, peaks for some researchers during this dose transition and typically resolves within two to three weeks

The combined effect of these modifications increase the drugs half-life from minutes to approximately 168 hours, enabling its once-weekly injection schedule an enormous improvement compared to the twice daily injection required for exenatide (Byetta) which was the first GLP-1 drug that was launched

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