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The effects of SGLT2s inhibitors on hemodynamics and glomerular hyperfiltration seem to be robust whereas those of GLP-1RAs have not been established
While the scale is one metric, seeing the physical changes in your silhouette over the coming months is incredibly motivating
Terami et al revealed that diabetes-induced disruption of the BBB allowed SGLT-2is to pass through in a dose-dependent manner
Actionables You can discuss the potential benefits of GLP-1 drugs with your healthcare provider if you're managing conditions like diabetes or struggling with mental health issues
Some report mild, transient nausea in the first 1 to 2 weeks that resolves spontaneously
The implication for clinical practice is that restoring youthful MOTS-c signaling might be a mechanistically legitimate target for longevity intervention
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