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Presences of complex groups in same molecule regulate chelation effects

2018 May 23;499(4):797802

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There is no benefit to reaching target dose faster if cardiovascular side effects become limiting

In mouse plasma degradation assay, the native peptide 1 had a half-life of 16 min and hybrids 2 , 5 and 9 had similar t 1/2 of 17, 23 and 17 min, respectively

The following organs were inspected: brain, heart, skin, liver, lungs, spleen, peritoneum, intestines, stomach, bladder, and kidneys