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CARB, a widely used chemotherapeutic agent, significantly impaired ovarian histoarchitecture, reduced follicle numbers at various developmental stages, and increased atretic follicles

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While glutathione itself crosses this barrier poorly, the brain can synthesize glutathione from precursor amino acids, and systemic glutathione elevation may indirectly support brain glutathione status through various mechanisms including reduced oxidative stress on blood-brain barrier integrity and improved availability of glutathione precursors

After heat-mediated antigen retrieval, slides were incubated with 1% bovine serum albumin to block nonspecific binding

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