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These lymphocytes then activate other lymphocytes to generate cytokines, such as interferon-, interleukin-4, and tumor necrosis factor (TNF- ), which damage the villi, resulting in enteritis

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High concentrations of copper can become toxic, since it can replace the iron in iron-sulfur clusters of proteins and damage or inactivate those proteins ( Interestingly, the mechanism behind the antimicrobial copper surfaces is different between wet- and dry-contact killing (Ramos-Ziga et al., 2023)

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