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Furthermore, age-related changes in gut microbiota favor microbiologic species that induce higher production of TMAO, correlating with the increase in endothelial dysfunction, subsequent atherosclerosis, and CVD associated with aging [61, 62, 64, 67]
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For many, it requires professional intervention
The SURPASS Phase 3 global clinical development project has enrolled more than 13,000 type 2 diabetes patients in 10 clinical trials, 5 of which are global registration studies