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3,4-Methylenedioxymethamphetamine (MDMA): stereoselective interactions at brain 5-HT1 and 5-HT2 receptors

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The mechanism of this is unknown but poor penetration of peripheral leptin to hypothalamic regions due to reduced capillary transport system in hypothalamic microcirculation could be responsible for its limited efficacy as an anti-obesity drug (47)

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Genetic polymorphism associated prefrontal glutathione and its coupling with brain glutamate and peripheral redox status in early psychosis