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If I experience severe nausea, which medication should we adjust first

Nevertheless, peptide-based obesity treatments are pushing forward

Dietary modifications that help: Eat smaller, more frequent meals instead of large ones Prioritize protein-forward meals, as protein is easier to digest when gastric emptying is slowed Avoid high-fat meals, which take longer to digest and can worsen nausea Eat slowly and stop before you feel full, as the sensation of fullness hits faster on retatrutide Stay hydrated with slow, steady sipping rather than drinking large amounts at once Timing strategies: Take your weekly injection at a consistent time each week Many researchers prefer evening injections so that the peak nausea period occurs during sleep Plan your dose increase days on weekends or rest days when GI symptoms are less disruptive Stay upright for at least 30 minutes after eating, as gravity helps with digestion when gastric emptying is slowed Natural remedies for mild nausea: Ginger has demonstrated anti-nausea properties in multiple studies and can help manage mild GI symptoms during dose transitions

When expanding trial eligibility criteria to reflect broader patient populations typically encountered in clinical practice, we identified 453,201 individuals initiating semaglutide or sitagliptin (expanding SUSTAIN-6 eligibility) and 136,089 initiating tirzepatide or dulaglutide (expanding SURPASS-CVOT eligibility)

Overall, future research should prioritize mechanistic elucidation, clinical translation, and optimization of therapeutic strategies to facilitate the development of precision medicine approaches in DKD

Were excited to share our new paper: Juvenile hormone and maternal egg care in the European earwig (Part II): Precocene exposure reduces post-oviposition egg care behaviours, just published in Hormones and Behavior