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Serious / Rare Side Effects Angioedema rare but life-threatening (less common than ACE inhibitors) Acute kidney injury especially in patients with bilateral renal artery stenosis Hyperkalemia requires monitoring 5

People taking heartburn medication, such as proton pump inhibitors, are at a higher risk for B12 deficiency and may benefit from alternative therapies to control/eliminate the heartburn or have regular Nutrient IV therapies and/or Vitamin B12 injections Elderly Vegans Vegetarians People with tapeworms Alcoholics Excessive use of antibiotics Excessive use of anti-convulsant medication Daily consumption of Aspirin may increase the risk for vitamin B12 deficiency

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And they stimulate the very L-cells that release GLP-1

Funding This study was funded by the National Natural Science Foundation of China (No

Systemic lupus erythematosus pathogenesis: interferon and beyond