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As-needed protocol: Use DSIP only during periods of elevated stress or sleep difficulty Maintain for 2-4 weeks as needed Discontinue when sleep normalizes This conservative approach treats DSIP as a targeted intervention rather than ongoing supplementation

Both arrive as lyophilized powder in compounded form

While platelet monitoring is required primarily for treatment safety, hepatic assessment is relevant both to detect valproate-induced hepatotoxicity and to screen for metabolic dysfunctionassociated steatotic liver disease (MASLD), a frequent complication of obesity and metabolic syndrome

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Same-day administration: Both compounds can be injected on the same day