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This means tongue darkening in Addison's disease is typically diffuse rather than focal, and it is almost always accompanied by other signs: darkening of skin creases, knuckles, scars, and other mucosal surfaces, along with systemic symptoms like fatigue, weight loss, low blood pressure, and salt cravings

Age-related changes in gut microbiome composition are also documented in peer-reviewed research

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[3] Controlled evidence demonstrating clinically meaningful weight loss from these injections is lacking

The news that weight-loss jabs are being investigated for potentially causing pancreatitis in hundreds of people may trigger a chorus of I told you so in people who are against obesity medicines on principle