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Effects on weight were seen primarily in people who took berberine in doses of more than 1 gram per day and for more than eight weeks

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Our results revealed that GEP44 did not promote internalization of Y2-R (Fig

For example, the mechanosensitive ion channel Piezo1 is markedly upregulated in the colonic mucosa of patients with UC (Zhou et al., 2025a), and its excessive activation exacerbates epithelial injury, in part by promoting ferroptosis (He H